Investigation in preterm neonates with jaundice requiring treatment

In this webinar, we shall discuss the investigations that are required in a preterm neonate with jaundice needing treatment
In addition to a full clinical examination, carry out all of the following tests in babies with significant jaundice requiring treatment: Total serum bilirubin for baseline level and to assess response to treatment. In general, TSB can be repeated every 12-24 hrs. As opposed to this, a baby with a setting for hemolysis such as Rh or ABO isoimmunisation would require TSB measurement repeat bilirubin estimation every 6-8 hours during initial 24 to 48 hours or so. In addition, the neonate should be investigated for: blood packed cell volume (PCV) or hemoglobin. blood group (mother and baby). DCT (Coombs’ test), if mother is O or Rh negative. Reticulocyte count and peripheral blood smear for evidence of hemolysis.
  • Introduction...
  • 1. Investigations ...
 

Introduction

Dr. C. APARNA
MD, DM (Neonatology)

Consultant Neonatologist
Ankura Hospital for Women and Children
Kukatpally, Hyderabad

1. Investigations in preterm neonates with jaundice requiring treatment

â–º Total serum bilirubin
      ♦ At baseline
      ♦ 12-24 hourly; 6-8 hrly in setting of hemolysis

â–º Blood packed cell volume (PCV) or hemoglobin

â–º Blood group (mother and baby)

â–º DCT (Coombs’ test), if mother is O group or Rh negative

â–º Reticulocyte count and peripheral blood smear for evidence
    of hemolysis

â–º Glucose 6 phosphate dehydrogenase (G6PD) levels